Exocytosis is a fundamental cellular process whereby secreted molecules are packaged into vesicles that move along cytoskeletal filaments and fuse with the plasma membrane.To function optimally, cells are strongly dependent on precisely controlled delivery of exocytotic cargo.In mammalian cells, microtubules serve as major tracks for vesicle transp
The effect of the magnetic field on the onset of thermal convection in a porous layer saturated by Jeffrey nanofluid is studied.Three distinct boundary conditions are considered to be free-free, rigid-rigid and rigid-free boundaries.The model used for Jeffrey nanofluid includes the effect of Brownian motion and thermophoresis.The normal mode analys
Dual-mobility (DM) implants have been used in total hip arthroplasty since 1974.Modular DM implants have seen an increase in use in primary and revision Cordial Glasses total hip arthroplasties given the theoretical decreased dislocation rate.DM constructs have 2 articulation sites, one between the acetabular shell and a polyethylene liner, as well
Dasatinib is a tyrosine kinase inhibitor CANDLES used for treatment of some specific types of leukaemia.The development of pleural effusion is a known adverse effect of dasatinib and chylothorax is exceptional.No case has been reported beyond 5 years of treatment and extensive search for an alternative diagnosis is currently suggested in such scena
The European Union (EU) imposed sanctions on Zimbabwe in 2002 and this article aims at evaluating the success of that decision.Applying a broader definition of success, this article assumes that sanctions can coerce, constrain and signal.Contrary to most of the literature holding that sanctions are imposed to change the behaviour of targets, this a